Volume 1 Issue 10
Oct.  2010
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Jingjing Tong, Xianghua Yan, Li Yu. The late stage of autophagy: cellular events and molecular regulation[J]. Protein&Cell, 2010, 1(10): 907-915. doi: 10.1007/s13238-010-0121-z
Citation: Jingjing Tong, Xianghua Yan, Li Yu. The late stage of autophagy: cellular events and molecular regulation[J]. Protein&Cell, 2010, 1(10): 907-915. doi: 10.1007/s13238-010-0121-z

The late stage of autophagy: cellular events and molecular regulation

doi: 10.1007/s13238-010-0121-z
  • Received Date: 2010-10-06
  • Rev Recd Date: 2010-10-18
  • Autophagy is an intracellular degradation system that delivers cytoplasmic contents to the lysosome for degradation. It is a "self-eating" process and plays a "house-cleaner" role in cells. The complex process consists of several sequential steps-induction, autophagosome formation, fusion of lysosome and autophagosome, degradation, efflux transportation of degradation products, and autophagic lysosome reformation. In this review, the cellular and molecular regulations of late stage of autophagy, including cellular events after fusion step, are summarized.
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