Volume 4 Issue 8
Aug.  2013
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Jia-Huai Wang. The sequence signature of an Ig-fold[J]. Protein&Cell, 2013, 4(8): 569-572. doi: 10.1007/s13238-013-3903-2
Citation: Jia-Huai Wang. The sequence signature of an Ig-fold[J]. Protein&Cell, 2013, 4(8): 569-572. doi: 10.1007/s13238-013-3903-2

The sequence signature of an Ig-fold

doi: 10.1007/s13238-013-3903-2
  • Ig superfamily (IgSF) constitutes the largest superfamily in human genome. In particular, Ig-like domains are the most abundant structural module within cell surface receptors, functioning in nervous as well as immune system. Here I describe some key sequence signature of an I-set Ig-like domain from known structures of IgSF members. These signature residues define the I-set Ig-like domain, which should aid structural and functional studies of cell surface receptors.
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    通讯作者: 陈斌, bchen63@163.com
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      沈阳化工大学材料科学与工程学院 沈阳 110142

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