Volume 6 Issue 4
Apr.  2015
Turn off MathJax
Article Contents
Jun Cao, Zhengyu Luo, Qingyu Cheng, Qianlan Xu, Yan Zhang, Fei Wang, Yan Wu, Xiaoyuan Song. Three-dimensional regulation of transcription[J]. Protein&Cell, 2015, 6(4): 241-253. doi: 10.1007/s13238-015-0135-7
Citation: Jun Cao, Zhengyu Luo, Qingyu Cheng, Qianlan Xu, Yan Zhang, Fei Wang, Yan Wu, Xiaoyuan Song. Three-dimensional regulation of transcription[J]. Protein&Cell, 2015, 6(4): 241-253. doi: 10.1007/s13238-015-0135-7

Three-dimensional regulation of transcription

doi: 10.1007/s13238-015-0135-7

This work was supported by grants from the National Natural Science Foundation of China (Grant No. 31472059), the National Key Scientific Program of China (No. 2015CB943000), the Fundamental Research Funds for the Central Universities (WK2070000034, WK2070000023) and the Major/Innovative Program of Development Foundation of Hefei Center for Physical Science and Technology (2014FXCX009) to XYS. XYS is a recipient of the Young Thousand Talents program (KJ2070000026).

  • Received Date: 2014-12-25
  • Rev Recd Date: 2015-01-09
  • Cells can adapt to environment and development by reconstructing their transcriptional networks to regulate diverse cellular processes without altering the underlying DNA sequences. These alterations, namely epigenetic changes, occur during cell division, differentiation and cell death. Numerous evidences demonstrate that epigenetic changes are governed by various types of determinants, including DNA methylation patterns, histone posttranslational modification signatures, histone variants, chromatin remodeling, and recently discovered chromosome conformation characteristics and noncoding RNAs (ncRNAs). Here, we highlight recent efforts on how the two latter epigenetic factors participate in the sophisticated transcriptional process and describe emerging techniques which permit us to uncover and gain insights into the fascinating genomic regulation.
  • loading
  • Relative Articles

    [1] Rujin Huang,  Jinyang Liu,  Xi Chen,  Ying Zhi,  Shuangyuan Ding,  Jia Ming,  Yulin Li,  Yangming Wang,  Jie Na. A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions. Protein&Cell, 2023, 14(2): 152-157.  doi: 10.1093/procel/pwac019
    [2] Yuliang Feng,  Xingguo Liu,  Siim Pauklin. 3D chromatin architecture and epigenetic regulation in cancer stem cells. Protein&Cell, 2021, 12(6): 440-454.  doi: 10.1007/s13238-020-00819-2
    [3] Lin-Yong Zhao,  Jinghui Song,  Yibin Liu,  Chun-Xiao Song,  Chengqi Yi. Mapping the epigenetic modifications of DNA and RNA. Protein&Cell, 2020, 11(11): 792-808.  doi: 10.1007/s13238-020-00733-7
    [4] Wenyuan Chen,  Hao Xiao,  Xurong Wang,  Shuanglin Song,  Zhen Han,  Xiaowu Li,  Fan Yang,  Li Wang,  Jingdong Song,  Hongrong Liu,  Lingpeng Cheng. Structural changes of a bacteriophage upon DNA packaging and maturation. Protein&Cell, 2020, 11(5): 374-379.  doi: 10.1007/s13238-020-00715-9
    [5] Wei Li,  Wenchen Shen,  Bo Zhang,  Kuan Tian,  Yamu Li,  Lili Mu,  Zhiyuan Luo,  Xiaoling Zhong,  Xudong Wu,  Ying Liu,  Yan Zhou. Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein&Cell, 2020, 11(3): 161-186.  doi: 10.1007/s13238-019-0650-z
    [6] Pengcheng Yang,  Li Hou,  Xianhui Wang,  Le Kang. Core transcriptional signatures of phase change in the migratory locust. Protein&Cell, 2019, 10(12): 883-901.  doi: 10.1007/s13238-019-0648-6
    [7] Xin Zhou,  Yu He,  Xiaofang Huang,  Yuting Guo,  Dong Li,  Junjie Hu. Reciprocal regulation between lunapark and atlastin facilitates ER three-way junction formation. Protein&Cell, 2019, 10(7): 510-525.  doi: 10.1007/s13238-018-0595-7
    [8] Tian-Lin Cheng,  Zilong Qiu. Long non-coding RNA tagging and expression manipulation via CRISPR/Cas9-mediated targeted insertion. Protein&Cell, 2018, 9(9): 820-825.  doi: 10.1007/s13238-017-0464-9
    [9] Chao Zhong,  Jinfang Zhu. Transcriptional regulators dictate innate lymphoid cell fates. Protein&Cell, 2017, 8(4): 242-254.  doi: 10.1007/s13238-017-0369-7
    [10] Qi Gu,  He Zhu,  Lei Chen,  Ling Shuai,  Jinhui Fang,  Jun Wu,  Lei Liu,  Wei Li,  Jianwu Dai,  Jie Hao,  Qi Zhou. Three dimensional collagen scaffolds promote iPSC induction with higher pluripotency. Protein&Cell, 2016, 7(11): 844-848.  doi: 10.1007/s13238-016-0321-2
    [11] Wenbo Li,  Wei Ding,  Gang Ji,  Li Wang,  Jianguo Zhang,  Fei Sun. Three-dimensional visualization of arsenic stimulated mouse liver sinusoidal by FIB-SEM approach. Protein&Cell, 2016, 7(3): 227-232.  doi: 10.1007/s13238-016-0246-9
    [12] Jing Li,  Yujing Zhang,  Dameng Li,  Yuchen Liu,  Danping Chu,  Xiaohong Jiang,  Dongxia Hou,  Ke Zen,  Chen-Yu Zhang. Small non-coding RNAs transfer through mammalian placenta and directly regulate fetal gene expression. Protein&Cell, 2015, 6(6): 391-396.  doi: 10.1007/s13238-015-0156-2
    [13] Lei Liu,  Nan Fang,  Yicheng Sun,  Huiying Yang,  Yiquan Zhang,  Yanping Han,  Dongsheng Zhou,  Ruifu Yang. Transcriptional regulation of the waaAE-coaD operon by PhoP and RcsAB in Yersinia pestis biovar Microtus. Protein&Cell, 2014, 5(12): 940-944.  doi: 10.1007/s13238-014-0110-8
    [14] Derong Xu,  Guifeng Wei,  Ping Lu,  Jianjun Luo,  Xiaomin Chen,  Geir Skogerbø,  Runsheng Chen. Analysis of the p53/CEP-1 regulated non-coding transcriptome in C. elegans by an NSR-seq strategy. Protein&Cell, 2014, 5(10): 770-782.  doi: 10.1007/s13238-014-0071-y
    [15] Hongwei Liang,  Junfeng Zhang,  Ke Zen,  Chen-Yu Zhang,  Xi Chen. Nuclear microRNAs and their unconventional role in regulating non-coding RNAs. Protein&Cell, 2013, 4(5): 325-330.  doi: 10.1007/s13238-013-3001-5
    [16] Jun Ma. Transcriptional activators and activation mechanisms. Protein&Cell, 2011, 2(11): 879-888.  doi: 10.1007/s13238-011-1101-7
    [17] Mo Xu,  Bing Zhu. Nucleosome assembly and epigenetic inheritance. Protein&Cell, 2010, 1(9): 820-829.  doi: 10.1007/s13238-010-0104-0
    [18] Shengnan Zhang,  Nan Zhong,  Fei Xue,  Xue Kang,  Xiaobai Ren,  Jiaxuan Chen,  Changwen Jin,  Zhiyong Lou,  Bin Xia. Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease. Protein&Cell, 2010, 1(4): 371-383.  doi: 10.1007/s13238-010-0044-8
    [19] Ping Chen,  Guohong Li. Dynamics of the higher-order structure of chromatin. Protein&Cell, 2010, 1(11): 967-971.  doi: 10.1007/s13238-010-0130-y
    [20] Jiyue Zhu,  Yuanjun Zhao,  Shuwen Wang. Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene. Protein&Cell, 2010, 1(1): 22-32.  doi: 10.1007/s13238-010-0014-1
  • 加载中


    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (224) PDF downloads(2000) Cited by()
    Proportional views


    DownLoad:  Full-Size Img  PowerPoint