Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach

Yuwei Bai; Shinya Tashiro; Satoru Nagatoishi; Toru Suzuki; Dongke Yan; Ruihua Liu; Kouhei Tsumoto; Mark Bartlam; Tadashi Yamamoto

doi:10.1007/s13238-015-0225-6

Volume 6 Issue 12

Dec. 2015

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Yuwei Bai, Shinya Tashiro, Satoru Nagatoishi, Toru Suzuki, Dongke Yan, Ruihua Liu, Kouhei Tsumoto, Mark Bartlam, Tadashi Yamamoto. Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach[J]. Protein&Cell, 2015, 6(12): 924-928. doi: 10.1007/s13238-015-0225-6

Citation:

Yuwei Bai, Shinya Tashiro, Satoru Nagatoishi, Toru Suzuki, Dongke Yan, Ruihua Liu, Kouhei Tsumoto, Mark Bartlam, Tadashi Yamamoto. Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach[J]. Protein&Cell, 2015, 6(12): 924-928. doi: 10.1007/s13238-015-0225-6

Citation:

Yuwei Bai, Shinya Tashiro, Satoru Nagatoishi, Toru Suzuki, Dongke Yan, Ruihua Liu, Kouhei Tsumoto, Mark Bartlam, Tadashi Yamamoto. Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach[J]. Protein&Cell, 2015, 6(12): 924-928. doi: 10.1007/s13238-015-0225-6

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Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach

doi: 10.1007/s13238-015-0225-6

1 State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China;
2 College of Life Sciences, Nankai University, Tianjin 300071, China;
3 Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan;
4 Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Onna-son, Kunigami, Okinawa 904-0412, Japan

Funds:

grant number 25121734 to TY)

and by funding from Okinawa Institute of Science and Technology Graduate University.

Platform for Drug Discovery, Informatics, and Structural Life Science from the Ministry of Education, Culture, Sports, Science and Technology, Japan (to KT)

by KAKENHI (Grants-in-Aid for Scientific Research on Innovative Areas

This work was supported by the National Basic Research Program (973 Program) (No. 2014CB560709 to MB)

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