Protein crystal quality oriented disulfide bond engineering

doi: 10.1007/s13238-017-0482-7

• Mengchen Pu^1,2 , 
• Zhijie Xu^2,3,6,7 , 
• Yao Peng^1,2,4,7 , 
• Yaguang Hou^2,3,6,7 , 
• Dongsheng Liu² , 
• Yang Wang⁵ , 
• Haiguang Liu^{5 ,}  , 
• Gaojie Song^{2 ,}  , 
• Zhi-Jie Liu^{1,2,4,6 ,} 

• 1 National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;

• 2 iHuman Institute, ShanghaiTech University, Shanghai 201210, China;

• 3 Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;

• 4 Insititute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650500, China;

• 5 Complex Systems Division, Beijing Computational Science Research Center, Beijing 100193, China;

• 6 School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;

• 7 University of Chinese Academy of Sciences, Beijing 100049, China