Volume 11 Issue 11
Nov.  2020
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Fan Yu, Te Li, Yanchao Sui, Qingxia Chen, Song Yang, Jia Yang, Renjie Hong, Dengwen Li, Xiumin Yan, Wei Zhao, Xueliang Zhu, Jun Zhou. O-GlcNAc transferase regulates centriole behavior and intraflagellar transport to promote ciliogenesis[J]. Protein&Cell, 2020, 11(11): 852-857. doi: 10.1007/s13238-020-00746-2
Citation: Fan Yu, Te Li, Yanchao Sui, Qingxia Chen, Song Yang, Jia Yang, Renjie Hong, Dengwen Li, Xiumin Yan, Wei Zhao, Xueliang Zhu, Jun Zhou. O-GlcNAc transferase regulates centriole behavior and intraflagellar transport to promote ciliogenesis[J]. Protein&Cell, 2020, 11(11): 852-857. doi: 10.1007/s13238-020-00746-2

O-GlcNAc transferase regulates centriole behavior and intraflagellar transport to promote ciliogenesis

doi: 10.1007/s13238-020-00746-2
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  • [1]
    Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820
    [2]
    Hardiville S, Hart GW (2014) Nutrient regulation of signaling, transcription, and cell physiology by O-GlcNAcylation. Cell Metab 20:208-213
    [3]
    Jiang J, Lazarus MB, Pasquina L, Sliz P, Walker S (2011) A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase. Nat Chem Biol 8:72-77
    [4]
    Jinek M, Rehwinkel J, Lazarus BD, Izaurralde E, Hanover JA, Conti E (2004) The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Nat Struct Mol Biol 11:1001-1007
    [5]
    Marquardt JR, Perkins JL, Beuoy KJ, Fisk HA (2016) Modular elements of the TPR domain in the Mps1 N terminus differentially target Mps1 to the centrosome and kinetochore. Proc Natl Acad Sci USA 113:7828-7833
    [6]
    Ran J, Liu M, Feng J, Li H, Ma H, Song T, Cao Y, Zhou P, Wu Y, Yang Y et al (2020) ASK1-mediated phosphorylation blocks HDAC6 ubiquitination and degradation to drive the disassembly of photoreceptor connecting cilia. Dev Cell 53(287-299):e285
    [7]
    Schou KB, Morthorst SK, Christensen ST, Pedersen LB (2014) Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8. Cilia 3:6
    [8]
    Tang Z, Lin MG, Stowe TR, Chen S, Zhu M, Stearns T, Franco B, Zhong Q (2013) Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites. Nature 502:254-257
    [9]
    Tugendreich S, Tomkiel J, Earnshaw W, Hieter P (1995) CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell 81:261-268
    [10]
    Yang X, Qian K (2017) Protein O-GlcNAcylation:emerging mechanisms and functions. Nat Rev Mol Cell Biol 18:452-465
    [11]
    Yang Y, Ran J, Liu M, Li D, Li Y, Shi X, Meng D, Pan J, Ou G, Aneja R et al (2014) CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6. Cell Res 24:1342-1353
    [12]
    Yang Y, Hao H, Wu X, Guo S, Liu Y, Ran J, Li T, Li D, Liu M, Zhou J (2019) Mixed-lineage leukemia protein 2 suppresses ciliary assembly by the modulation of actin dynamics and vesicle transport. Cell Discov 5:33
    [13]
    Yu F, Ran J, Zhou J (2016) Ciliopathies:does hdac6 represent a new therapeutic target? Trends Pharmacol Sci 37:114-119
    [14]
    Yu F, Guo S, Li T, Ran J, Zhao W, Li D, Liu M, Yan X, Yang X, Zhu X et al (2019) Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications. Cell Res 29:171-173
    [15]
    Zhao H, Zhu L, Zhu Y, Cao J, Li S, Huang Q, Xu T, Huang X, Yan X, Zhu X (2013) The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis. Nat Cell Biol 15:1434-1444
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