Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons

doi: 10.1007/s13238-020-00820-9

• Dandan Liang^1,2,3 , 
• Zhigang Xue^4,5 , 
• Jinfeng Xue⁴ , 
• Duanyang Xie^1,2,3 , 
• Ke Xiong^1,2,3 , 
• Huixing Zhou^1,2,3 , 
• Fulei Zhang^1,2,3 , 
• Xuling Su^1,2,3 , 
• Guanghua Wang^1,2,3 , 
• Qicheng Zou^1,2,3 , 
• Yi Liu^1,2,3 , 
• Jian Yang^1,2,3 , 
• Honghui Ma^1,2,3 , 
• Luying Peng^1,2,3,6 , 
• Chunyu Zeng⁷ , 
• Gang Li⁸ , 
• Li Wang⁹ , 
• Yi-Han Chen^{1,2,3,6 ,  ,} 

• 1 Department of Cardiology, East Hospital, Tongji University School of Medicine, Shanghai 200120, China;

• 2 Key Laboratory of Arrhythmias of the Ministry of Education of China, Tongji University School of Medicine, Shanghai 200120, China;

• 3 Institute of Medical Genetics, Tongji University, Shanghai 200092, China;

• 4 Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai 200092, China;

• 5 Reproductive Medicine Center, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China;

• 6 Department of Pathology and Pathophysiology, Tongji University School of Medicine, Shanghai 200092, China;

• 7 Department of Cardiology, Daping Hospital, Chongqing 400042, China;

• 8 Department of Neurology, East Hospital, Tongji University School of Medicine, Shanghai 200120, China;

• 9 State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China