Volume 12 Issue 7
Jul.  2021
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Bin Zhou. Sinoatrial node pacemaker cells: cardiomyocyte-or neuron-like cells?[J]. Protein&Cell, 2021, 12(7): 518-519. doi: 10.1007/s13238-021-00827-w
Citation: Bin Zhou. Sinoatrial node pacemaker cells: cardiomyocyte-or neuron-like cells?[J]. Protein&Cell, 2021, 12(7): 518-519. doi: 10.1007/s13238-021-00827-w

Sinoatrial node pacemaker cells: cardiomyocyte-or neuron-like cells?

doi: 10.1007/s13238-021-00827-w

Bin Zhou is supported by National Science Foundation of China (8208810001).

  • Publish Date: 2021-07-08
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  • [1]
    Cingolani E, Goldhaber JI, Marbán E (2018) Next-generation pacemakers:from small devices to biological pacemakers. Nat Rev Cardiol 15:139-150
    De Ponti R, Marazzato J, Bagliani G, Leonelli FM, Padeletti L (2018) Sick sinus syndrome. Card Electrophysiol Clin 10:183-195
    Galang G, Mandla R, Ruan H, Jung C, Sinha T, Stone NR, Wu RS, Mannion BJ, Allu PKR, Chang K et al (2020) ATAC-Seq reveals an Isl1 enhancer that regulates sinoatrial node development and function. Circ Res. 127:1502-1518
    Herring N, Kalla M, Paterson DJ (2019) The autonomic nervous system and cardiac arrhythmias:current concepts and emerging therapies. Nat Rev Cardiol 16:707-726
    John RM, Kumar S (2016) Sinus node and atrial arrhythmias. Circulation 133:1892-1900
    Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ (2019) 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay:A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol 74:e51-e156
    Lakatta EG, Maltsev VA, Vinogradova TM (2010) A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks control the timekeeping mechanism of the heart's pacemaker. Circ Res 106:659-673
    Linscheid N, Logantha SJRJ, Poulsen PC, Zhang S, Schrölkamp M, Egerod KL, Thompson JJ, Kitmitto A, Galli G, Humphries MJ (2019) Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking. Nat Commun. 10:2889
    Lisman J, Cooper K, Sehgal M, Silva AJ (2018) Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability. Nat Neurosci 21:309-314
    Mesirca P, Fedorov VV, Hund TJ, Torrente AG, Bidaud I, Mohler PJ, Mangoni ME (2020) Pharmacologic approach to sinoatrial node dysfunction. Annu Rev Pharmacol Toxicol. https://doi.org/10.1146/annurev-pharmtox-031120-115815
    Peters CH, Sharpe EJ, Proenza C (2020) Cardiac pacemaker activity and aging. Annu Rev Physiol 82:21-43
    Protze SI, Liu J, Nussinovitch U, Ohana L, Backx PH, Gepstein L, Keller GM (2017) Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker. Nat Biotechnol 35:56-68
    Satoh H (2003) Sino-atrial nodal cells of mammalian hearts:ionic currents and gene expression of pacemaker ionic channels. J Smooth Muscle Res 39:175-193
    Sharma S, Drezner JA, Baggish A, Papadakis M, Wilson MG, Prutkin JM, La Gerche A, Ackerman MJ, Borjesson M, Salerno JC (2018) International recommendations for electrocardiographic interpretation in athletes. Eur Heart J 39:1466-1480
    Shen MJ, Zipes DP (2014) Role of the autonomic nervous system in modulating cardiac arrhythmias. Circ Res 114:1004-1021
    Van Eif VW, Devalla HD, Boink GJ, Christoffels VM (2018) Transcriptional regulation of the cardiac conduction system. Nat Rev Cardiol 15:617-630
    Yaniv Y, Ahmet I, Liu J, Lyashkov AE, Guiriba TR, Okamoto Y, Ziman BD, Lakatta EG (2014) Synchronization of sinoatrial node pacemaker cell clocks and its autonomic modulation impart complexity to heart beating intervals. Heart Rhythm 11:1210-1219
    Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M (2017) Mammalian γ2 AMPK regulates intrinsic heart rate. Nat Commun 8:1258
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