Volume 13 Issue 3
Mar.  2022
Turn off MathJax
Article Contents
Jinghui Lei, Xiaoyu Jiang, Wei Li, Jie Ren, Datao Wang, Zhejun Ji, Zeming Wu, Fang Cheng, Yusheng Cai, Zheng-Rong Yu, Juan Carlos Izpisua Belmonte, Chunyi Li, Guang-Hui Liu, Weiqi Zhang, Jing Qu, Si Wang. Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis[J]. Protein&Cell, 2022, 13(3): 220-226. doi: 10.1007/s13238-021-00860-9
Citation: Jinghui Lei, Xiaoyu Jiang, Wei Li, Jie Ren, Datao Wang, Zhejun Ji, Zeming Wu, Fang Cheng, Yusheng Cai, Zheng-Rong Yu, Juan Carlos Izpisua Belmonte, Chunyi Li, Guang-Hui Liu, Weiqi Zhang, Jing Qu, Si Wang. Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis[J]. Protein&Cell, 2022, 13(3): 220-226. doi: 10.1007/s13238-021-00860-9

Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis

doi: 10.1007/s13238-021-00860-9
  • loading
  • [1]
    Bi S, Liu Z, Wu Z, Wang Z, Liu X, Wang S, Ren J, Yao Y, Zhang W, Song M et al (2020) SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer. Protein Cell 11:483-504
    [2]
    Geng L, Liu Z, Zhang W, Li W, Wu Z, Wang W, Ren R, Su Y, Wang P, Sun L et al (2019) Chemical screen identifies a geroprotective role of quercetin in premature aging. Protein Cell 10:417-435
    [3]
    Jeon OH, Kim C, Laberge RM, Demaria M, Rathod S, Vasserot AP, Chung JW, Kim DH, Poon Y, David N et al (2017) Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment. Nat Med 23:775-781
    [4]
    Kalluri R, LeBleu VS (2020) The biology, function, and biomedical applications of exosomes. Science 367:eaau6977
    [5]
    Lei J, Wang S, Kang W, Chu Q, Liu Z, Sun L, Ji Y, Esteban CR, Yao Y, Belmonte JCI et al (2021a) FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction. Protein Cell 12:145-151
    [6]
    Lei Q, Gao F, Liu T, Ren W, Chen L, Cao Y, Chen W, Guo S, Zhang Q, Chen W et al (2021b) Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow-derived mesenchymal stem cells and slow age-related degeneration. Sci Transl Med 13:eaaz8697
    [7]
    Rong X, Chu W, Zhang H, Wang Y, Qi X, Zhang G, Wang Y, Li C (2019) Antler stem cell-conditioned medium stimulates regenerative wound healing in rats. Stem Cell Res Ther 10:326
    [8]
    Rong X, Yang Y, Zhang G, Zhang H, Li C, Wang Y (2020) Antler stem cells as a novel stem cell source for reducing liver fibrosis. Cell Tissue Res 379:195-206
    [9]
    Sui Z, Sun H, Weng Y, Zhang X, Sun M, Sun R, Zhao B, Liang Z, Zhang Y, Li C et al (2020) Quantitative proteomics analysis of deer antlerogenic periosteal cells reveals potential bioactive factors in velvet antlers. J Chromatogr A 1609:
    [10]
    Tran C, Damaser MS (2015) Stem cells as drug delivery methods:application of stem cell secretome for regeneration. Adv Drug Deliv Rev 82-83:1-11
    [11]
    Wang D, Berg D, Ba H, Sun H, Wang Z, Li C (2019) Deer antler stem cells are a novel type of cells that sustain full regeneration of a mammalian organ-deer antler. Cell Death Dis 10:443
    [12]
    Xu M, Bradley EW, Weivoda MM, Hwang SM, Pirtskhalava T, Decklever T, Curran GL, Ogrodnik M, Jurk D, Johnson KO et al (2017) Transplanted senescent cells induce an osteoarthritis-like condition in mice. J Gerontol A 72:780-785
    [13]
    Yao B, Zhang M, Leng X, Liu M, Liu Y, Hu Y, Zhao D, Zhao Y (2018) Antler extracts stimulate chondrocyte proliferation and possess potent anti-oxidative, anti-inflammatory, and immune-modulatory properties. In Vitro Cell Dev Biol Anim 54:439-448
    [14]
    Yin K, Wang S, Zhao RC (2019) Exosomes from mesenchymal stem/stromal cells:a new therapeutic paradigm. Biomark Res 7:8
    [15]
    Zhang J, Liu GH, Qu J, Song M (2020) Treating osteoarthritis via gene therapy with rejuvenation factors. Gene Ther 27:309-311
  • PAC-0220-21262-LGH_supple (5).xls
    PAC-0220-21262-LGH_supple (4).xls
    PAC-0220-21262-LGH_supple (2).xls
    PAC-0220-21262-LGH_supple (1).xls
    PAC-0220-21262-LGH_supple (3).xls
    PAC-0220-21262-LGH_supple (1).pdf
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)

    Article Metrics

    Article views (320) PDF downloads(33) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return