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“Magic Bullets” at the center stage of immune therapy: a special issue on therapeutic antibodies
Zhiqiang An
2018, 9(1): 1-2. DOI: 10.1007/s13238-017-0488-1
[Abstract] [PDF]
In vitro-engineered non-antibody protein therapeutics
Rudo Simeon, Zhilei Chen
2018, 9(1): 3-14. DOI: 10.1007/s13238-017-0386-6
[Abstract] [PDF]
Pharmacokinetics of monoclonal antibodies and Fc-fusion proteins
Liming Liu
2018, 9(1): 15-32. DOI: 10.1007/s13238-017-0408-4
[Abstract] [PDF]
Antibody-drug conjugates: recent advances in conjugation and linker chemistries
Kyoji Tsuchikama, Zhiqiang An
2018, 9(1): 33-46. DOI: 10.1007/s13238-016-0323-0
[Abstract] [PDF]
Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy
Yusuke Mimura, Toshihiko Katoh, Radka Saldova, Roisin O'Flaherty, Tomonori Izumi, Yuka Mimura-Kimura, Toshiaki Utsunomiya, Yoichi Mizukami, Kenji Yamamoto, Tsuneo Matsumoto, Pauline M. Rudd
2018, 9(1): 47-62. DOI: 10.1007/s13238-017-0433-3
[Abstract] [PDF]
IgG Fc engineering to modulate antibody effector functions
Xinhua Wang, Mary Mathieu, Randall J. Brezski
2018, 9(1): 63-73. DOI: 10.1007/s13238-017-0473-8
[Abstract] [PDF]
Molecular and functional analysis of monoclonal antibodies in support of biologics development
Xin Wang, Zhiqiang An, Wenxin Luo, Ningshao Xia, Qinjian Zhao
2018, 9(1): 74-85. DOI: 10.1007/s13238-017-0447-x
[Abstract] [PDF]
Current progress in innovative engineered antibodies
R. Strohl William
2018, 9(1): 86-120. DOI: 10.1007/s13238-017-0457-8
[Abstract] [FullText HTML] [PDF]
Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig
Philip D. Bardwell, Matthew M. Staron, Junjian Liu, Qingfeng Tao, Susanne Scesney, Gail Bukofzer, Luis E. Rodriguez, Chee-Ho Choi, Jennifer Wang, Qing Chang, Feng Dong, Cherrie Donawho, Jieyi Wang, Christine M. Grinnell, Edit Tarcsa, Charles Hutchins, Tariq Ghayur, Jijie Gu
2018, 9(1): 121-129. DOI: 10.1007/s13238-017-0429-z
[Abstract] [PDF]
A novel therapeutic anti-HBV antibody with increased binding to human FcRn improves in vivo PK in mice and monkeys
Ciming Kang, Lin Xia, Yuanzhi Chen, Tianying Zhang, Yiwen Wang, Bing Zhou, Min You, Quan Yuan, Chi-Meng Tzeng, Zhiqiang An, Wenxin Luo, Ningshao Xia
2018, 9(1): 130-134. DOI: 10.1007/s13238-017-0438-y
[Abstract] [PDF]
Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab
Shuguang Tan, Kefang Liu, Yan Chai, Catherine W. -H. Zhang, Shan Gao, George F. Gao, Jianxun Qi
2018, 9(1): 135-139. DOI: 10.1007/s13238-017-0412-8
[Abstract] [PDF]